Detailed SMPC and OD register data for: PYRUKYND
Data as extracted from Orphan Designation Register
Product (OD)
PYRUKYND
PL number (OD)
PLGB 52779/0001
OD Designation ID (OD)
Active substance (OD)
Mitapivat sulfate Potent, allosteric activator of wild-type red blood cell (RBC)-specific form of pyruvate kinase (PKR) and a range of mutant PKR enzymes. Mitapivat targets the underlying enzymatic defect that causes haemolysis in pyruvate kinase deficiency by restoring the activity of mutant forms of PKR.
Data as extracted from SMPC. (PS: More information at bottom of the page)
Product (SMPC)
PL Number (SMPC)
Composition/ Active Substance (SMPC)
Dose form (SMPC)
Marketing Authorisation holder details (SMPC)
AI match to EMA Substance Dictionary
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SMPC composition / active substance
Matched EMA substance
EMA SMS ID
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Further information for:
Select a section below to read the detailed content extracted from the SMPC / Orphan Designation register.
OD Indication (OD)
Pyrukynd is indicated for the treatment of pyruvate kinase deficiency (PK deficiency) in adult patients
Full Designation Number(OD)
PLGB 52779/0001-0005OD1
Orphan Condition(OD)
pyruvate kinase deficiency (PK deficiency)
All Indications (SMPC)
All Contraindications (SMPC)
Warnings/Precautions (SMPC)
Interactions (SMPC)
Pregnancy/Lactation (SMPC)
Driving/Machines (SMPC)
Undesirable effects (SMPC)
Overdose (SMPC)
Shelf life (SMPC)
Storage (SMPC)
Container description (SMPC)
Handling/Disposal (SMPC)
SMPC_URL